Blood Analysis : The interpretation of norms and values: COMMON SENSE

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- In Caucasian populations of the Mediterranean world, there are 85% of individuals with dark hair, 15% with light hair.

To an outside observer, individuals with light hair, might be considered 'unconventional', and should color their hair!

 - In Caucasian populations the Scandinavian world, there are 85% of individuals with light hair, 15% with dark hair. 

To an outside observer, individuals with dark hair, could be considered 'unconventional', and should to bleach their hair!

- A person aged 80 with dark hair....should be bleach hair because the populations of 80 years have gray hair!!!

This is ABSURD! NONSENSE!

Yet it is a rough illustration of the interpretation of standards for normal values of blood parameters!

Let me be clear! The aim of this paper is to examine and ask reflection on values, limits, results in the limit of 'exacting standards' or 'borderline'. Where, only one parameter is highlighted, without clinical schedule.

These results often appear during a routine check, not justified by a particular disease

Frankly abnormal results reinforced by other symptoms must be treated with the utmost seriousness!

In control tests, the parameter most often highlighted is ... cholesterol!

Reinforced by the opinions of the doctor ... it does not commit to anything you say to watch your diet ... he knows that 99 percent of the time, you go and say you eat poorly.

And ... your doctor will advise you, or prescribe medication....

Before taking these drugs:

Some questions to ask you:

Is this the first time?

What were your previous values?

How have they evolved?

What are the values of your parents?

What are your eating habits?

Under which conditions the sample has been collected?

Because you should know that these compounds ; Statins and Fibrates ;are not safe! They have side-effects!

These side effects are more important and more dangerous than your cholesterol a little 'high'!

Recent studies tend to show that the action of these drugs is unrelated to the incidence of deaths caused by cholesterol!

Instead, these molecules, one after the other, are criticized by the medical profession because of side effects.

... between 1994 and 2006, the percentage of men aged 65 to 74 with "high cholesterol" fell from 87% to 54% ... Despite this, the rate of coronary heart disease in this age group remained almost identical!

The American Heart Association recommends that your total cholesterol is less than 200 mg / dL, but what they do not tell you is that total cholesterol is about worthless in determining your risk of heart disease, if not above 330.

In addition, the AHA updating their guidelines in 2004, lowering the recommended level of LDL from 130 to less than 100 or less than 70 for patients at very high risk.

Many of the scientists who helped develop the guidelines even admitted that the scientific evidence supporting the less than-70 recommendation was not very convinced. American Heart Association (23 January 2006)

Eight of the nine doctors on the team that developed the new lines cholesterol guidelines had been paid by pharmaceutical companies that manufacture statin cholesterol-lowering drugs. (American Heart Association, "What Your Cholesterol Level Means,)

TOTAL CHOLESTEROL LEVELS vs MORTALITY DATA from 164 COUNTRIES

For full display (pdf) fellow this link: http://renegadewellness.files.wordpress.com/2011/02/cholesterol-mortality-chart.pdf

In 1987, in the Journal of the American Medical Association Framingham Study investigators reported these two important findings:

 1) Over age 50 there is no increased overall mortality with either high or low serum cholesterol levels,

2) In people with a falling cholesterol level (over the first 14 years of the study), for each 1% mg/dl drop in cholesterol there was an 11 percent increase in all-cause mortality over the next 18 years. (JAMA 1987;257:2176-2180)

note: this is based on this study that the 'big Pharma "have developped cholesterol myth!!!!

 Cholesterol is a natural substance, present in every cell membrane in our bodies and is essential for normal cell function. It’s also a basic building block of many essential hormones in your body, as well as vitamin D. So the mainstream's old adage that cholesterol is all bad is only misguided!

Since Big Pharma and the mainstream medias has left no stone unturned in convincing people that Statins Therapy is the only effective way to protect their heart health,

From to the latest results from an Australian study, this may very well come as a surprise to you...

Australian researchers analyzed the results of 14 international studies, over the past 55 years, which looked at the heart protective benefits of lycopene. Lycopene is the powerful antioxidant that gives ripe tomatoes their bright red color. Previous research has already shown that it’s essential for good health, since it helps lower the risk of heart attacks and strokes.  Lycopene have the same  potency as statins against cholesterol levels... but  is natural!

In conclusion, a little common sense!

 - Ask your doctor about the balance between the result a bit limited and the risk of side effects of medication

The reality , it is that the Big Pharma’s profit-driven plan to flood the market with dangerous drugs, like cholesterol-lowering statins, that cause a wide range of dangerous side effects like muscle pain, liver dysfunction, kidney failure, depression and cancer to name but a few...

Nobody died from eating tomatoes!!

 We also want to alert people to the fact that cholesterol is not the villain the mainstream medias are trying to make it out to be — one of the many myths

http://forum.lowcarber.org/showthread.php?t=430996

No life without Cholesterol!

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Cholesterol has been one of the most maligned and misunderstood substances of the twentieth century. Eating foods high in cholesterol was long thought to raise blood cholesterol levels, something considered to be so dangerous that some of the most nutritious foods on the planet -- like liver and egg yolks -- were demonized as enemies of our arteries.

Unfortunately the campaign against cholesterol has washed away from our daily menus many of the most important foods we should treasure for excellent health and vitality

The Facts

Cholesterol is a major constituent of each vegetal or animal cell !

Cholesterol is found in every cell of your body. It is especially abundant in the membranes of these cells, where it helps maintain the integrity of these membranes, and plays a role in facilitating cell signaling-- meaning the ability of your cells to communicate with each other so you function as a human, rather than a pile of cells. Molecule for molecule, cholesterol can make up nearly half of the cell membrane. Since it is smaller and weighs less than other molecules in the cell membrane, it makes up a lesser proportion of the cell membrane's mass, usually roughly 20 percent.

Cholesterol is also present in membranes of organelles inside the cells, although it usually makes up a smaller proportion of the membrane.

Cholesterol is an amphipathic molecule, meaning, like phospholipids, it contains a hydrophilic and a hydrophobic portion. Cholesterol's hydroxyl (OH) group aligns with the phosphate heads of the phospholipids. The remaining portion of it tucks into the fatty acid portion of the membrane.

By stabilizing certain proteins together in lipid rafts, cholesterol is important to helping these proteins maintain their function.

This could range from forming blood clots or thinning blood, to allowing sugar into your cells, to burning fat, to regulating calcium in your blood, and literally includes, in some way, most of the functions in your body. (¹)

Cholesterol Is Necessary for Digestion

The human body uses cholesterol to synthesize bile acids, which are important for the digestion of fats. The primary bile acid, cholic acid, is very similar in structure to cholesterol.

in order for the human digestive system to digest fats, they must be emulsified into the digestive juices, because the enzymes that break them down are water-soluble.

Bile acid synthesis is up-regulated by cholesterol and down-regulated by cholic acid. This means that the higher the cholesterol to cholic acid ratio is, the faster bile acids will be produced. As bile acids are produced, and the concentration of cholesterol lowers and the concentration of cholic acid rises, bile acid synthesis slows down.(²)

Vitamin D is Synthesized From Cholesterol

One of cholesterol's many functions in the body is to act as a precursor to vitamin D. Since cholesterol is a precursor to vitamin D, inhibiting the synthesis of cholesterol will also inhibit the synthesis of vitamin D. Since sunlight is required to turn cholesterol into vitamin D, avoiding the sun will likewise undermine our ability to synthesize vitamin D. And since vitamin D-rich foods are also rich in cholesterol, low-cholesterol diets are inherently deficient in vitamin D.(3)

Vitamin D is best known for its role in calcium metabolism and bone health, but new roles are continually being discovered for it, including roles in mental health, blood sugar regulation, the immune system, and cancer prevention.

Vitamin D3

When atmospheric conditions are ideal and skies are clear, 30 minutes of whole-body exposure of pale skin to sunlight without clothing or sunscreen can result in the synthesis of between 10,000 and 20,000 IU of vitamin D. These quantities of vitamin D are large, and therefore capable of supplying the body's full needs (4)

Synthesis of Steroid Hormones From Cholesterol

Cholesterol is the precursor to a hormone called pregnenolone, which has important functions itself, but is also the precursor to all other steroid hormones.

Pregnenolone is converted to progesterone, a sex hormone, which in turn is converted into cortisol, which regulates inflammation and blood sugar, aldosterone, which regulates mineral balance and blood pressure, or testosterone, a type of sex hormone referred to as an androgen, which regulates libido, muscle mass, and plays other roles.  testosterone is further modified, undergoing conversion to estradiol, a different type of sex hormone called an estrogen. (5)

 

The Myth:

Eating Cholesterol-Rich Foods Raises Blood Cholesterol Levels

The myth goes something like this: arteries are like pipes; cholesterol is gooey, sticky gunk. When you eat cholesterol, it winds up in your blood. If the cholesterol level in your blood gets too high, it starts caking up the pipes. Thus, if you don't want your pipes clogged, don't eat foods rich in cholesterol.

Such is the basic logic behind advice to avoid eating nutrient-dense foods

The truth :

Eating Cholesterol Does Not Raise Blood Cholesterol Levels

The truth is, however, that there is no direct connection between the amount of cholesterol you eat and the concentration of cholesterol in your blood. In most people, eating cholesterol has little or no effect on this amount. In about 30 percent of the population, eating cholesterol does in fact increase the concentration of cholesterol in the blood — but it increases the "good" cholesterol.

To put it in more scientific terms, eating cholesterol "results in a less atherogenic lipoprotein profile."

LDL Particle Size

Moreover, the actual number of LDL particles do not change at all; they just get bigger. When your doctor measures your blood cholesterol level, the lab reports it by weight. In America, this is usually in milligrams per deciliter. When your "cholesterol level" is high, this means that in a given measure of blood volume (such as a deciliter or a tenth of a liter) the total number of cholesterol-carrying lipoprotein particles weigh more. This could mean that you have more particles, or it could mean that the particles weigh more because they are carrying more cholesterol.

According to research, it is the small, dense LDL particles that raise the risk of atherosclerosis, while the large, buoyant LDL particles are safe. This may be because small, dense LDL particles are much more vulnerable to oxidation. People whose LDL is primarily small and dense have three times the risk of heart disease as people whose LDL is primarily large and buoyant.

In the egg-feeding studies, egg consumption makes the LDL particles of the "hyperresponders" get bigger, not more numerous. When they get bigger, they become less subject to oxidation and accumulation in atherosclerotic plaque

In over two thirds of the population, then, egg consumption leads to little or no change in cholesterol at all. In less than a third of the population, total cholesterol goes up, but both the ratio of LDL to HDL and the total number of LDL particles remains the same; the LDL particles just get bigger and safer.

If arteries were like pipes and cholesterol was like gunk, more gunk would just clog up the pipe — but arteries are nothing like pipes and cholesterol is nothing like gunk. Consider the myth busted.

References

(1)    Alberts, et al., Molecular Biology of the Cell: Fourth Edition, New York: Garland Science, 2002,.

(2)  (5) Harvey et al., Biochemistry: 3rd Edition, Baltimore: Lippincott Wiliams and Wilkins, 2005

(3)    Cannel, John, "Vit D: When Why Where and How Much," Wise Traditions 2005 November 12, 2005 (lecture).

(4)    Adams and Hollis, "Vitamin D: Synthesis, Metabolism, and Clinical Measurement." In: Coe and Favus, eds., Disorders of Bone and Mineral Metabolism, Philadelphia: Lippincott Williams and Wilkins (2002) p. 159.

(5)     

(6)    (7) Fernandez ML. Dietary cholesterol provided by eggs and plasma lipoproteins in healthy populations. Curr Opin Clin Nutr Metab Care. 2006;9:8-12.

Analyses sanguines : L’interprétation des normes et valeurs : du bon sens !!

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Dans les populations de race blanche du monde méditerranéen , il y a 85 % des individus avec des cheveux foncés, 15% avec des cheveux clairs ; Pour un observateur étranger, les individus aux cheveux clairs , pourraient être  considérés comme ‘hors normes’, et devraient se colorer les cheveux ! Dans les populations de race blanche du monde scandinave, il y a 85 % des individus avec des cheveux clairs, 15% avec des cheveux foncés ; Pour un observateur étranger, les individus aux cheveux foncé , pourraient être  considérés comme ‘hors normes’, et devraient se décolorer les cheveux !

Une personne de 80 ans avec des cheveux  foncés, devrait se décolorer les cheveux parce que  la population de 80 ans a en général les cheveux gris !

C’est ABSURDE !  Un  NON SENS !

C’est pourtant une illustration grossière de l’interprétation des normes relatives aux valeurs normales de certains paramètres sanguins !

Je veux être clair !  le but de cet article est d’examiner et de poser la réflexion au sujet des valeurs  ‘ limites’, des résultats à la limite des ‘normes standards’ ou ‘ border line’. Où un seul paramètre est mis en évidence, sans tableau clinique annexe.

Ces résultats apparaissent souvent lors d’un contrôle de routine, non justifiés par une pathologie particulière

Les résultats franchement anormaux renforcés par d’autres symptômes doivent êtres traités avec le plus grand sérieux !

Lors des tests de contrôle, le paramètre le plus souvent mis en évidence c’est … le cholestérol !  

Regarder l'emission de france2 au sujet du cholestérol  du 17/09/2012
le cholestérol et les medicaments inutiles ( le sujet commence à 7min 30)
http://www.france2.fr/videos/69571384

Renforcer par les opinions du médecin … cela ne l’engage à rien de vous dire de surveiller votre alimentation … il sait que 99 fois sur cent , vous aller dire que vous mangez mal , que vous fumez….

Et… votre médecin va vous  conseiller, ou vous prescrire un traitement médicamenteux

Avant de prendre ces médicaments :

Quelques questions à vous poser au sujet des valeurs ‘anormales’ :

Est-ce  c’est la première fois ?

Quelles étaient  vos valeurs antérieures ?

Comment ont-elles évolués

Quels sont les valeurs de vos parents ?

Quelles sont vos habitudes alimentaires ?

Dans quelles conditions le prélèvement a-t-il été réalisé ?

Car, vous devez savoir que ces composés  ( statines et fibrates)  ne sont pas sans risques !Ils présentent des effets secondaires non négligeables !

Ces effets secondaires sont plus importants et plus dangereux que votre cholestérol ‘ un peu ‘haut’ !

Des études récentes  tendent à démontrer que l’action de ces médicaments est sans relation  avec l’incidence des décès  causés par le cholestérol !

Au contraire , ces  molécules , les unes après les autres, sont critiquées par le corps médical, en raison des effets secondaires.

... entre 1994 et 2006, le pourcentage d'hommes âgés de 65 à 74 avec «un cholestérol élevé » a diminué de 87% à 54% ... Malgré cela, le taux de maladie coronarienne pour ce groupe d'âge resté à peu près identique !!

L'American Heart Association recommande que votre taux de cholestérol total soit inférieur à 200 mg / dL, mais ce qu'ils ne vous disent pas, c'est que le taux de cholestérol total est à peu près sans valeur dans la détermination de votre risque de maladie cardiaque, si ce n'est au-dessus de 330.

En outre, l'AHA en mettant  à jour leurs lignes directrices en 2004, en abaissant le niveau recommandé de LDL de 130 à moins de 100, voire moins de 70 pour les patients à très haut risque.

Plusieurs des scientifiques qui ont contribué à élaborer les lignes directrices ont même admis que la preuve scientifique étayant la recommandation moins que-70 n'était pas très forte. ( American Heart Association Janvier 23, 2006)

Huit des neuf médecins de l’équipe qui a élaboré les lignes nouvelles directrices de cholestérol avaient été rémunérés par des compagnies pharmaceutiques qui fabriquent des statines médicaments hypocholestérolémiants.(  American Heart Association, "What Your Cholesterol Level Means,)

En conclusion, un peu de bon sens !  demandez à votre médecin la balance entre un résultat un peu limite et les risques d’effets secondaire d’un traitement médicamenteux

Souvenez-vous du Médiator !.....